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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSME4Proteasome activator complex subunit 4. (1823 aa)    
Predicted Functional Partners:
PSMB2
Proteasome subunit beta.
    
 0.978
PSMD4
26S proteasome non-ATPase regulatory subunit 4 isoform X1.
    
 0.975
PSMA5
Proteasome subunit alpha type.
    
 0.966
PSMA4
Proteasome subunit alpha type.
    
 0.966
PSMB4
Proteasome subunit beta; Belongs to the peptidase T1B family.
    
 0.964
PSMB5
Proteasome subunit beta.
    
 0.937
PSMA6
Proteasome subunit alpha type.
    
 0.923
ENSVVUP00000027737
annotation not available
    
 0.923
PSMB6
Proteasome subunit beta.
    
 0.923
ENSVVUP00000030237
annotation not available
    
 0.912
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.