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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDC42EP5Cdc42 effector protein 5. (149 aa)    
Predicted Functional Partners:
LENG8
LOW QUALITY PROTEIN: leukocyte receptor cluster member 8.
      
 0.799
TTYH1
Protein tweety homolog; Probable chloride channel.
      
 0.756
LAIR1
Leukocyte-associated immunoglobulin-like receptor 1 isoform X1.
      
 0.747
TTC13
Tetratricopeptide repeat protein 13.
      
 0.729
DNAJC3
dnaJ homolog subfamily C member 3.
      
 0.607
LOC112909395
LOW QUALITY PROTEIN: V-set and transmembrane domain-containing protein 1-like.
      
 0.604
CDC42EP2
Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family.
     
 0.573
CDC42EP3
Cdc42 effector protein 3.
     
 0.550
SEPTIN11
Septin-11 isoform X5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
    
 
 0.529
MPPE1
Metallophosphoesterase 1 isoform X1.
      
 0.519
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.