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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SACSSacsin. (4528 aa)    
Predicted Functional Partners:
RNF216
E3 ubiquitin-protein ligase RNF216 isoform X1.
    
 0.787
OTUD4
OTU domain-containing protein 4.
   
 
 0.774
INCENP
Inner centromere protein isoform X1.
   
 0.770
DIABLO
Diablo homolog, mitochondrial.
    
 0.752
AURKC
Aurora kinase C; Belongs to the protein kinase superfamily.
   
 0.657
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.657
AURKB
Aurora kinase B isoform X3; Belongs to the protein kinase superfamily.
   
 0.657
ATP5F1B
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 0.653
CDCA8
Borealin.
   
 0.653
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
   
 0.651
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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