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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKXcAMP-dependent protein kinase catalytic subunit PRKX; Belongs to the protein kinase superfamily. (333 aa)    
Predicted Functional Partners:
PRKAR1A
cAMP-dependent protein kinase type I-alpha regulatory subunit.
 
 
 0.962
ENSVVUP00000003300
annotation not available
 
 
 0.878
PRKAR2A
cAMP-dependent protein kinase type II-alpha regulatory subunit.
 
 
 0.860
PRKAR2B
cAMP-dependent protein kinase type II-beta regulatory subunit.
 
 
 0.816
PRKAR1B
cAMP-dependent protein kinase type I-beta regulatory subunit.
 
 
 0.780
GYG2
Glycogenin-2 isoform X1.
   
  
 0.743
PKIA
cAMP-dependent protein kinase inhibitor; Belongs to the PKI family.
   
 
 0.741
PLN
Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
    
 0.714
AKAP1
A-kinase anchor protein 1, mitochondrial.
    
 0.678
CNBD2
Cyclic nucleotide-binding domain-containing protein 2.
   
 0.667
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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