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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP4K1Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (789 aa)    
Predicted Functional Partners:
GRAP2
GRB2-related adapter protein 2.
   
 
 0.873
GRB2
Growth factor receptor-bound protein 2.
   
 
 0.689
CRK
Adapter molecule crk isoform X1.
    
 
 0.587
LCP2
Lymphocyte cytosolic protein 2.
   
 
 0.560
CRKL
Crk-like protein.
    
 
 0.541
NCK1
Cytoplasmic protein.
    
 
 0.527
RASGRP4
RAS guanyl-releasing protein 4 isoform X2.
   
 
 0.522
PDIA6
Protein disulfide-isomerase A6; Belongs to the protein disulfide isomerase family.
    
 
 0.514
PELI1
E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
      
 0.455
EVI2B
Protein EVI2B.
      
 0.451
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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