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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIAM2T-lymphoma invasion and metastasis-inducing protein 2 isoform X1. (1458 aa)    
Predicted Functional Partners:
GRIN1
Glutamate receptor ionotropic, NMDA 1 isoform X1.
   
 
 0.602
RAC3
Ras-related C3 botulinum toxin substrate 3.
    
 0.566
RAC1
Ras-related C3 botulinum toxin substrate 1.
    
 0.566
RAC2
Ras-related C3 botulinum toxin substrate 2.
    
 0.566
RHOU
Rho-related GTP-binding protein RhoU.
    
 0.559
RHOJ
Rho-related GTP-binding protein RhoJ.
    
 0.554
RHOF
Rho-related GTP-binding protein RhoF.
    
 0.545
ENSVVUP00000007132
annotation not available
    
 0.533
ELL3
RNA polymerase II elongation factor ELL3 isoform X2.
   
  
 0.533
ENSVVUP00000019958
annotation not available
    
 0.533
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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