close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC3Probable E3 ubiquitin-protein ligase HERC3 isoform X1. (1006 aa)    
Predicted Functional Partners:
ISG15
Ubiquitin-like protein ISG15.
   
 0.711
NAP1L5
Nucleosome assembly protein 1-like 5; Belongs to the nucleosome assembly protein (NAP) family.
      
 0.607
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X2.
   
 
 0.593
RCC1
Regulator of chromosome condensation isoform X1.
    
0.567
EXOC6B
Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
      
 0.563
SH3RF1
E3 ubiquitin-protein ligase SH3RF1.
    
 0.535
TECRL
trans-2,3-enoyl-CoA reductase-like.
      
 0.529
INO80E
INO80 complex subunit E.
    
 
 0.525
ASB4
Ankyrin repeat and SOCS box protein 4.
    
 
 0.524
ZADH2
Prostaglandin reductase 3.
      
 0.524
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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