STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNAJC5DnaJ heat shock protein family (Hsp40) member C5. (198 aa)    
Predicted Functional Partners:
HSPA8
Uncharacterized protein; Belongs to the heat shock protein 70 family.
  
 0.974
ENSUAMP00000005986
V-SNARE coiled-coil homology domain-containing protein.
   
 0.920
SYT2
Synaptotagmin 2.
   
 0.898
SLC32A1
Solute carrier family 32 member 1.
   
 0.894
TFIP11
Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...]
    
 
 0.886
CDC5L
Cell division cycle 5 like.
   
 
 0.882
RAB3A
RAB3A, member RAS oncogene family.
     
 0.880
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
   
 
 0.861
PLRG1
Pleiotropic regulator 1.
    
 
 0.856
PRPF19
Pre-mRNA processing factor 19.
    
 
 0.854
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.