STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C12orf45Chromosome 12 open reading frame 45. (185 aa)    
Predicted Functional Partners:
NOP58
NOP58 ribonucleoprotein.
   
 
 0.755
THEM4
Thioesterase superfamily member 4.
      
 0.746
PALMD
Palmdelphin.
     
 0.746
ENSUAMP00000013646
Uncharacterized protein.
    
 
 0.632
RWDD1
RWD domain containing 1.
      
 0.624
ENSUAMP00000024212
Uncharacterized protein.
   
    0.589
ZNHIT3
Zinc finger HIT-type containing 3.
      
 0.587
NUFIP1
Nuclear FMR1 interacting protein 1.
    
 0.551
RUVBL2
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
   
 
 0.538
IL20RA
Interleukin 20 receptor subunit alpha.
      
 0.518
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.