STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RASGEF1CRasGEF domain family member 1C. (466 aa)    
Predicted Functional Partners:
ISOC1
Isochorismatase domain containing 1.
      
 0.743
LIX1
Limb and CNS expressed 1.
      
 0.739
MAP10
Microtubule associated protein 10.
      
 0.680
FAM13B
Family with sequence similarity 13 member B.
      
 0.675
ENSUAMP00000014890
Phosphoinositide phospholipase C.
      
 0.635
RUFY1
RUN and FYVE domain containing 1.
      
 0.613
CASZ1
Castor zinc finger 1.
      
 0.570
KCNS2
Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family.
      
 0.559
ZSCAN2
Zinc finger and SCAN domain containing 2.
      
 0.527
DGUOK
Deoxyguanosine kinase.
   
  
 0.527
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.