STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD50Ankyrin repeat domain 50. (1429 aa)    
Predicted Functional Partners:
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.774
SNX27
Sorting nexin 27.
    
 
 0.766
CFAP52
Cilia and flagella associated protein 52.
    
 0.732
VPS26B
VPS26, retromer complex component B.
    
 
 0.717
FKBP15
Peptidylprolyl isomerase.
   
 
 0.684
ENSUAMP00000009902
Metallophos_2 domain-containing protein.
   
 
 0.677
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.677
PPP6C
Serine/threonine-protein phosphatase.
    
 0.666
SNX2
Sorting nexin 2.
   
 0.660
MYO3B
Myosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.658
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.