STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTHCystathionine gamma-lyase. (409 aa)    
Predicted Functional Partners:
ENSUAMP00000012599
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.999
MTR
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.991
MPST
Sulfurtransferase.
  
 
 0.987
MTHFR
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 0.980
TST
Sulfurtransferase.
  
 
 0.976
BCAT2
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 0.970
ENSUAMP00000024756
GST C-terminal domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.969
GOT2
Aspartate aminotransferase.
   
 
 0.968
AHCY
Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.
  
 0.967
CDO1
Cysteine dioxygenase.
     
 0.966
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.