STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSUAMP00000010541ZnMc domain-containing protein. (499 aa)    
Predicted Functional Partners:
TIMP4
TIMP metallopeptidase inhibitor 4.
    
 0.480
TIMP2
TIMP metallopeptidase inhibitor 2.
    
 0.455
HEATR9
HEAT repeat containing 9.
      
 0.447
SPP1
Secreted phosphoprotein 1.
     
 0.438
TIMP3
TIMP metallopeptidase inhibitor 3.
    
 0.436
ETNK2
Ethanolamine kinase 2.
   
  
 0.424
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
   
 
  0.420
ENSUAMP00000022960
Uncharacterized protein.
   
 
  0.420
TMEM189-UBE2V1
TMEM189-UBE2V1 readthrough.
   
 
  0.420
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.