STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK20Cyclin dependent kinase 20; Belongs to the protein kinase superfamily. (346 aa)    
Predicted Functional Partners:
CCNH
Cyclin H; Belongs to the cyclin family.
    
 0.925
MNAT1
MNAT1 component of CDK activating kinase.
   
 0.881
GTF2H3
General transcription factor IIH subunit 3.
    
 0.877
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit.
    
 0.876
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.875
ENSUAMP00000005997
HTH TFE/IIEalpha-type domain-containing protein.
    
 0.862
ENSUAMP00000004809
General transcription factor IIH subunit.
   
 0.857
GTF2H1
General transcription factor IIH subunit 1.
   
 0.854
POLR2C
RNA polymerase II subunit C.
   
 0.781
POLR2D
RNA polymerase II subunit D.
   
 0.775
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.