STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CA3Carbonic anhydrase 3; Belongs to the alpha-carbonic anhydrase family. (260 aa)    
Predicted Functional Partners:
RPF2
Ribosome production factor 2 homolog.
   
 
 0.586
BHMT2
Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.
      
 0.580
BHMT
Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.
      
 0.580
GRWD1
Glutamate rich WD repeat containing 1.
   
  
 0.515
NRIP3
Nuclear receptor interacting protein 3.
      
 0.511
RRS1
Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.
   
 
 0.503
CKM
Creatine kinase, M-type; Belongs to the ATP:guanido phosphotransferase family.
   
 
 0.493
ENSUAMP00000001516
Ribosomal_L18_c domain-containing protein.
    
 
 0.485
CA4
Carbonic anhydrase 4; Belongs to the alpha-carbonic anhydrase family.
  
 
0.485
SLC13A5
Solute carrier family 13 member 5.
   
  
 0.484
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.