STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHDC1Kelch domain containing 1. (268 aa)    
Predicted Functional Partners:
ENSUAMP00000012029
Uncharacterized protein.
    
   0.521
POLE2
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
    
   0.513
GRN
Granulin precursor.
    
   0.513
SLC25A1
Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.
    
   0.513
CS
Citrate synthase; Belongs to the citrate synthase family.
    
   0.513
CXorf56
Chromosome X open reading frame 56.
    
   0.513
ENSUAMP00000005084
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 
 0.471
CSNK2A2
Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.
    
 
 0.471
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 
 0.451
RNF7
Ring finger protein 7.
    
 0.441
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.