STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDH22Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins. (801 aa)    
Predicted Functional Partners:
PEX11A
Peroxisomal biogenesis factor 11 alpha.
      
 0.725
GLRX2
Glutaredoxin 2.
      
 0.672
TMEM241
Transmembrane protein 241.
      
 0.583
DNTTIP1
Deoxynucleotidyltransferase terminal interacting protein 1.
      
 0.572
ADAM30
ADAM metallopeptidase domain 30.
   
 
 0.563
DLEU7
Deleted in lymphocytic leukemia 7.
      
 0.551
CYP2W1
Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family.
      
 0.526
DEGS2
Delta 4-desaturase, sphingolipid 2.
      
 0.522
ENSUAMP00000011014
Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.
    
 
 0.510
PKP4
Plakophilin 4.
    
 0.504
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.