STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSUAMP00000015967Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (258 aa)    
Predicted Functional Partners:
F2RL2
Coagulation factor II thrombin receptor like 2.
    
  0.907
F2R
Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.895
SPINK1
Serine peptidase inhibitor, Kazal type 1.
   
 0.885
F2RL1
F2R like trypsin receptor 1.
   
 0.882
F2RL3
F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
  0.865
ENSUAMP00000001987
Peptidase S1 domain-containing protein.
  
  
 
0.837
APP
Amyloid beta precursor protein.
    
 0.836
ENSUAMP00000023927
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
  
 
0.836
ENSUAMP00000023928
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
  
 
0.833
ENSUAMP00000008799
BPTI/Kunitz inhibitor domain-containing protein.
    
 0.741
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.