STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDGFHeparin binding growth factor. (239 aa)    
Predicted Functional Partners:
CDK13
Cyclin dependent kinase 13.
    
 
 0.570
CDK12
Cyclin dependent kinase 12.
    
 
 0.570
PTN
Pleiotrophin.
   
  
 0.566
MDK
Midkine.
      
 0.541
GAPT
GRB2 binding adaptor protein, transmembrane.
      
 0.520
SMYD1
SET and MYND domain containing 1.
   
 
 0.507
CDYL
Chromodomain Y like.
   
 
 0.497
ENSUAMP00000029322
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 
 0.454
CCNT2
Cyclin T2; Belongs to the cyclin family.
   
 
 0.428
CCNK
Cyclin K; Belongs to the cyclin family.
   
 
 0.428
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.