STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)    
Predicted Functional Partners:
P2RX7
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
  
  
0.968
P2RX3
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
  
  
0.944
ENSUAMP00000005541
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
 
0.939
P2RX4
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
  
0.938
ENSUAMP00000017678
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
  
 
0.931
ENSUAMP00000008651
Uncharacterized protein.
     
 0.922
ENSUAMP00000025740
Uncharacterized protein.
     
 0.917
GRIN2A
Glutamate ionotropic receptor NMDA type subunit 2A.
   
 
 0.909
GRIN1
Glutamate ionotropic receptor NMDA type subunit 1.
   
 
 0.906
CHEK2
Checkpoint kinase 2.
   
 0.774
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.