STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PYGO2Pygopus family PHD finger 2. (369 aa)    
Predicted Functional Partners:
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.746
BCL9
BCL9 transcription coactivator.
    
  0.538
CTNNB1
Catenin beta 1.
   
 0.523
TCF7L2
Transcription factor 7 like 2.
    
  0.506
TLE4
TLE family member 4, transcriptional corepressor.
     
  0.500
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.439
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.438
TLE3
TLE family member 3, transcriptional corepressor.
     
  0.438
BCL9L
BCL9 like.
     
 0.434
ENSUAMP00000025748
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 0.428
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.