STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HAS2Hyaluronan synthase 2. (541 aa)    
Predicted Functional Partners:
UGDH
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
 
 0.765
TNFAIP6
TNF alpha induced protein 6.
   
  
 0.734
ENSUAMP00000027942
Link domain-containing protein.
      
 0.698
HACL1
2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family.
  
 
 0.640
ILVBL
IlvB acetolactate synthase like; Belongs to the TPP enzyme family.
  
 
 0.640
HYAL4
Hyaluronidase.
   
  
 0.608
PTX3
Pentraxin 3.
   
  
 0.586
ENSUAMP00000035883
Hyaluronidase.
   
  
 0.581
HYAL3
Hyaluronidase.
   
  
 0.581
SPAM1
Hyaluronidase.
   
  
 0.580
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.