STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NMNAT2Nicotinamide nucleotide adenylyltransferase 2. (307 aa)    
Predicted Functional Partners:
NAMPT
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
   
 
 0.956
NMRK1
Nicotinamide riboside kinase 1.
  
 
 0.950
NADSYN1
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
  
 
 0.947
NAPRT
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 
 0.943
SIRT1
Sirtuin 1.
    
 0.940
QPRT
Quinolinate phosphoribosyltransferase.
    
 0.938
SIRT3
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
    
 0.934
NADK
NAD kinase.
  
 
 0.929
ENSUAMP00000026000
Uncharacterized protein.
     
 0.927
NT5C
5', 3'-nucleotidase, cytosolic.
     
 0.922
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.