STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOX10SRY-box transcription factor 10. (465 aa)    
Predicted Functional Partners:
MBP
Myelin basic protein.
   
 
 0.818
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
     
 0.795
PAX3
Paired box 3.
   
 
 0.790
PLP1
Proteolipid protein 1.
   
  
 0.787
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
 
 0.767
OLIG2
Oligodendrocyte transcription factor 2.
   
 0.764
EGR2
Early growth response 2.
    
 0.754
DCT
Dopachrome tautomerase.
   
 0.752
DLX2
Distal-less homeobox 2.
    
 
 0.744
ASCL1
Achaete-scute family bHLH transcription factor 1.
    
 
 0.740
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.