STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GNSN-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (551 aa)    
Predicted Functional Partners:
GUSB
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
  
 0.967
GLB1
Beta-galactosidase.
   
 0.959
ENSUAMP00000002767
Glyco_hydro_20 domain-containing protein.
   
 0.955
ENSUAMP00000033771
Beta-hexosaminidase.
   
 0.954
ENSUAMP00000003463
Uncharacterized protein.
   
 
 0.789
AP1S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
     
 0.789
AP1G2
AP-1 complex subunit gamma.
     
 0.782
CTSZ
Cathepsin Z; Belongs to the peptidase C1 family.
   
 0.772
DNASE2B
Deoxyribonuclease 2 beta.
   
 0.725
ENSUAMP00000016390
Sulfatase domain-containing protein.
  
 
 0.694
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.