STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSUAMP00000029400Uncharacterized protein. (499 aa)    
Predicted Functional Partners:
ENSUAMP00000006744
Uncharacterized protein.
 
  
 
0.994
ENSUAMP00000027175
Uncharacterized protein.
    
 0.965
SYNPO
Synaptopodin.
    
 0.965
CTNNB1
Catenin beta 1.
    
 0.961
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.961
ACTN4
Actinin alpha 4.
    
 0.957
ENSUAMP00000031589
Uncharacterized protein.
    
 0.956
MAGI3
Membrane associated guanylate kinase, WW and PDZ domain containing 3.
  
 
0.949
PRKCI
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.947
ENSUAMP00000032923
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.945
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.