STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLX6Distal-less homeobox 6. (291 aa)    
Predicted Functional Partners:
DLX5
Distal-less homeobox 5.
   
 
0.788
BMP2
Bone morphogenetic protein 2.
     
 0.472
SP9
Sp9 transcription factor.
    
 
 0.465
FAM241B
Family with sequence similarity 241 member B.
      
 0.461
ADGRD1
Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.
      
 0.439
GTF2I
General transcription factor IIi.
      
 0.429
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.