STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NUCKS1Nuclear casein kinase and cyclin dependent kinase substrate 1. (243 aa)    
Predicted Functional Partners:
ENSUAMP00000024186
Uncharacterized protein.
      
 0.634
NEK5
NIMA related kinase 5.
      
 0.630
ZNF593
Zinc finger protein 593.
      
 0.600
RAB29
RAB29, member RAS oncogene family.
 
 
  
 0.588
APBB3
Amyloid beta precursor protein binding family B member 3.
   
  
 0.534
RIOK2
RIO kinase 2.
      
 0.532
ENSUAMP00000005801
Uncharacterized protein.
      
 0.531
ZNF446
Zinc finger protein 446.
      
 0.528
KLHL28
Kelch like family member 28.
      
 0.518
ENSUAMP00000010575
Uncharacterized protein.
      
 0.495
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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