STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDLIM7PDZ and LIM domain 7. (458 aa)    
Predicted Functional Partners:
RSU1
Ras suppressor protein 1.
      
 0.633
DDI1
DNA damage inducible 1 homolog 1.
      
 0.607
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
   
 0.575
NCKAP1L
NCK associated protein 1 like.
   
 
 0.544
TBX4
T-box transcription factor 4.
   
 
 0.543
DBNL
Drebrin like.
 
 
  
 0.543
ENSUAMP00000018309
Uncharacterized protein.
   
  
 0.543
ARHGAP6
Rho GTPase activating protein 6.
    
 
 0.541
ENSUAMP00000032828
Uncharacterized protein.
      
 0.540
ENSUAMP00000001886
Uncharacterized protein.
      
 0.533
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.