STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C18orf21Chromosome 18 open reading frame 21. (227 aa)    
Predicted Functional Partners:
RPRD1A
Regulation of nuclear pre-mRNA domain containing 1A.
      
 0.675
RNF41
Ring finger protein 41.
      
 0.626
RPP25
Ribonuclease P and MRP subunit p25.
   
   0.578
RASSF2
Ras association domain family member 2.
      
 0.558
ANKRD52
Ankyrin repeat domain 52.
      
 0.558
MOCOS
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
      
 0.532
SLC23A2
Solute carrier family 23 member 2.
      
 0.495
GALNT1
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.459
ENSUAMP00000033827
Uncharacterized protein.
      
 0.459
TMEFF2
Transmembrane protein with EGF like and two follistatin like domains 2.
      
 0.444
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.