STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BCL2A1BCL2 related protein A1. (174 aa)    
Predicted Functional Partners:
BCL2L11
BCL2 like 11.
    
 0.956
BAK1
BCL2 antagonist/killer 1.
    
 
 0.949
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 0.943
PMAIP1
Phorbol-12-myristate-13-acetate-induced protein 1.
    
 0.923
ENSUAMP00000035027
Uncharacterized protein.
   
 0.901
BMF
Bcl2 modifying factor.
    
 0.866
BAD
BCL2 associated agonist of cell death.
   
 0.777
APAF1
Apoptotic peptidase activating factor 1.
    
 0.666
BECN2
Beclin 2.
    
 0.597
BECN1
Beclin 1.
    
 0.597
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.