STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSUAMP00000032486G_PROTEIN_RECEP_F1_2 domain-containing protein. (305 aa)    
Predicted Functional Partners:
TRPV1
Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.599
TRPA1
Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.530
GPR139
G protein-coupled receptor 139.
      
 0.520
UTS2B
Urotensin 2B.
     
 0.493
SCN10A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
     
 0.468
LPAR5
Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family.
     
 0.468
ENSUAMP00000036797
Ion_trans domain-containing protein.
      
 0.459
TRPM8
LSDAT_euk domain-containing protein.
      
 0.459
LAMP5
Lysosomal associated membrane protein family member 5.
      
 0.452
CYSLTR2
Cysteinyl leukotriene receptor 2.
      
 0.405
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.