STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSUAMP00000032511Protein kinase domain-containing protein. (132 aa)    
Predicted Functional Partners:
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
   
 0.994
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
0.994
NFKBIA
NFKB inhibitor alpha.
    
 0.987
TNFRSF1A
TNF receptor superfamily member 1A.
   
 0.985
RELA
RELA proto-oncogene, NF-kB subunit.
    
 0.978
NFKB1
Nuclear factor kappa B subunit 1.
   
 0.968
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
   
 0.968
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
   
 0.958
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.954
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.951
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.