STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATL1Atlastin GTPase 1. (558 aa)    
Predicted Functional Partners:
SPAST
Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...]
   
 
 0.769
REEP1
Receptor expression-enhancing protein.
    
 
 0.768
RTN2
Reticulon.
    
 
 0.767
REEP4
Receptor expression-enhancing protein.
   
 
 0.765
REEP3
Receptor expression-enhancing protein.
   
 
 0.738
ARL14
ADP ribosylation factor like GTPase 14; Belongs to the small GTPase superfamily. Arf family.
   
 
 0.727
RTN4
Reticulon.
    
 
 0.676
RTN3
Reticulon.
    
 
 0.670
REEP2
Receptor expression-enhancing protein.
    
 
 0.652
SPART
Spartin.
      
 0.634
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.