STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSUAMP00000035192Uncharacterized protein. (82 aa)    
Predicted Functional Partners:
HIF1A
Hypoxia inducible factor 1 subunit alpha.
   
 0.993
ENSUAMP00000021070
Uncharacterized protein.
   
 0.987
EPAS1
Endothelial PAS domain protein 1.
   
 0.986
NPAS4
Neuronal PAS domain protein 4.
    
 0.985
HIF3A
Hypoxia inducible factor 3 subunit alpha.
   
 0.951
NPAS1
Neuronal PAS domain protein 1.
    
 0.937
CREBBP
CREB binding protein.
   
 0.892
EP300
E1A binding protein p300.
   
 0.892
ENSUAMP00000028801
BHLH domain-containing protein.
   
 0.863
ENSUAMP00000028802
Uncharacterized protein.
   
 0.810
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.