STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIGFPhosphatidylinositol glycan anchor biosynthesis class F. (219 aa)    
Predicted Functional Partners:
PIGO
Phosphatidylinositol glycan anchor biosynthesis class O.
    
 0.969
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
   
 
 0.968
PIGT
Phosphatidylinositol glycan anchor biosynthesis class T.
     
 0.964
GPAA1
Glycosylphosphatidylinositol anchor attachment 1.
     
 0.953
PIGS
Phosphatidylinositol glycan anchor biosynthesis class S.
     
 0.952
PIGG
Phosphatidylinositol glycan anchor biosynthesis class G.
    
 0.950
PIGU
Phosphatidylinositol glycan anchor biosynthesis class U.
     
 0.949
ENSUAMP00000010908
Mannosyltransferase.
     
 0.916
ENSUAMP00000025955
Uncharacterized protein.
     
 0.916
ALG11
ALG11 alpha-1,2-mannosyltransferase.
      
 0.828
Your Current Organism:
Ursus americanus
NCBI taxonomy Id: 9643
Other names: American black bear, Euarctos americanus, U. americanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.