node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDC6 | CDT1 | ENSAMEP00000008326 | ENSAMEP00000000390 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Chromatin licensing and DNA replication factor 1. | 0.999 |
CDC6 | GMNN | ENSAMEP00000008326 | ENSAMEP00000010724 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Geminin DNA replication inhibitor. | 0.783 |
CDC6 | MCM3 | ENSAMEP00000008326 | ENSAMEP00000009027 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDC6 | MCM4 | ENSAMEP00000008326 | ENSAMEP00000001715 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDC6 | MCM5 | ENSAMEP00000008326 | ENSAMEP00000001534 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.997 |
CDC6 | MCM6 | ENSAMEP00000008326 | ENSAMEP00000006194 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDC6 | MCM7 | ENSAMEP00000008326 | ENSAMEP00000011780 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.998 |
CDC6 | ORC1 | ENSAMEP00000008326 | ENSAMEP00000009783 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.999 |
CDC6 | ORC3 | ENSAMEP00000008326 | ENSAMEP00000004795 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 3. | 0.999 |
CDC6 | ORC4 | ENSAMEP00000008326 | ENSAMEP00000014134 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.999 |
CDT1 | CDC6 | ENSAMEP00000000390 | ENSAMEP00000008326 | Chromatin licensing and DNA replication factor 1. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.999 |
CDT1 | GMNN | ENSAMEP00000000390 | ENSAMEP00000010724 | Chromatin licensing and DNA replication factor 1. | Geminin DNA replication inhibitor. | 0.998 |
CDT1 | MCM3 | ENSAMEP00000000390 | ENSAMEP00000009027 | Chromatin licensing and DNA replication factor 1. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDT1 | MCM4 | ENSAMEP00000000390 | ENSAMEP00000001715 | Chromatin licensing and DNA replication factor 1. | DNA helicase; Belongs to the MCM family. | 0.999 |
CDT1 | MCM5 | ENSAMEP00000000390 | ENSAMEP00000001534 | Chromatin licensing and DNA replication factor 1. | DNA helicase; Belongs to the MCM family. | 0.999 |
CDT1 | MCM6 | ENSAMEP00000000390 | ENSAMEP00000006194 | Chromatin licensing and DNA replication factor 1. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDT1 | MCM7 | ENSAMEP00000000390 | ENSAMEP00000011780 | Chromatin licensing and DNA replication factor 1. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.998 |
CDT1 | ORC1 | ENSAMEP00000000390 | ENSAMEP00000009783 | Chromatin licensing and DNA replication factor 1. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.998 |
CDT1 | ORC3 | ENSAMEP00000000390 | ENSAMEP00000004795 | Chromatin licensing and DNA replication factor 1. | Origin recognition complex subunit 3. | 0.997 |
CDT1 | ORC4 | ENSAMEP00000000390 | ENSAMEP00000014134 | Chromatin licensing and DNA replication factor 1. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.998 |