PHF21A protein (Ailuropoda melanoleuca) - STRING interaction network

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Score

PHF21A

PHD finger protein 21A. (628 aa)

Predicted Functional Partners:

RCOR1

0.978

KDM1A

0.974

HMG20B

0.970

HDAC1

0.742

RCOR3

0.727

HMG20A

0.724

G1LWP6_AILME

0.724

RCOR2

0.724

HDAC2

0.665

MTA1

0.664

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G1LWP6_AILME	HDAC1	ENSAMEP00000011499	ENSAMEP00000008076	HMG box domain-containing protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.499
G1LWP6_AILME	HDAC2	ENSAMEP00000011499	ENSAMEP00000013919	HMG box domain-containing protein.	Histone deacetylase 2.	0.499
G1LWP6_AILME	HMG20B	ENSAMEP00000011499	ENSAMEP00000006015	HMG box domain-containing protein.	High mobility group 20B.	0.706
G1LWP6_AILME	KDM1A	ENSAMEP00000011499	ENSAMEP00000015737	HMG box domain-containing protein.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.664
G1LWP6_AILME	PHF21A	ENSAMEP00000011499	ENSAMEP00000000630	HMG box domain-containing protein.	PHD finger protein 21A.	0.724
G1LWP6_AILME	RCOR1	ENSAMEP00000011499	ENSAMEP00000019245	HMG box domain-containing protein.	REST corepressor 1.	0.651
G1LWP6_AILME	RCOR2	ENSAMEP00000011499	ENSAMEP00000019133	HMG box domain-containing protein.	REST corepressor 2.	0.520
G1LWP6_AILME	RCOR3	ENSAMEP00000011499	ENSAMEP00000001165	HMG box domain-containing protein.	REST corepressor 3.	0.658
HDAC1	G1LWP6_AILME	ENSAMEP00000008076	ENSAMEP00000011499	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	HMG box domain-containing protein.	0.499
HDAC1	HDAC2	ENSAMEP00000008076	ENSAMEP00000013919	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2.	0.993
HDAC1	HMG20A	ENSAMEP00000008076	ENSAMEP00000008792	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	High mobility group 20A.	0.499
HDAC1	HMG20B	ENSAMEP00000008076	ENSAMEP00000006015	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	High mobility group 20B.	0.744
HDAC1	KDM1A	ENSAMEP00000008076	ENSAMEP00000015737	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.841
HDAC1	MTA1	ENSAMEP00000008076	ENSAMEP00000000074	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Metastasis associated 1.	0.867
HDAC1	PHF21A	ENSAMEP00000008076	ENSAMEP00000000630	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	PHD finger protein 21A.	0.742
HDAC1	RCOR1	ENSAMEP00000008076	ENSAMEP00000019245	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	REST corepressor 1.	0.955
HDAC1	RCOR2	ENSAMEP00000008076	ENSAMEP00000019133	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	REST corepressor 2.	0.564
HDAC1	RCOR3	ENSAMEP00000008076	ENSAMEP00000001165	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	REST corepressor 3.	0.638
HDAC2	G1LWP6_AILME	ENSAMEP00000013919	ENSAMEP00000011499	Histone deacetylase 2.	HMG box domain-containing protein.	0.499
HDAC2	HDAC1	ENSAMEP00000013919	ENSAMEP00000008076	Histone deacetylase 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.993