STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (478 aa)    
Predicted Functional Partners:
ANGPTL4
Angiopoietin like 4.
    
 0.990
G1LV85_AILME
UPAR/Ly6 domain-containing protein.
    
 0.989
ANGPTL3
Angiopoietin like 3.
    
 0.966
LRP1
LDL receptor related protein 1.
    
 0.940
LPIN1
Lipin 1.
     
 0.929
LIPC
Lipase C, hepatic type.
  
  
0.925
MGLL
Monoglyceride lipase.
     
 0.923
APOH
Apolipoprotein H.
    
 0.918
APOE
Apolipoprotein E.
     
 0.914
MOGAT3
Monoacylglycerol O-acyltransferase 3.
   
 
 0.912
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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