STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RENRenin; Belongs to the peptidase A1 family. (407 aa)    
Predicted Functional Partners:
ATP6AP2
ATPase H+ transporting accessory protein 2.
   
 0.998
AGT
Angiotensinogen; Belongs to the serpin family.
   
 0.966
AGTR2
Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.852
NR3C2
Nuclear receptor subfamily 3 group C member 2.
    
 
 0.788
ACE2
Angiotensin-converting enzyme.
      
 0.745
INS-IGF2
INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 0.731
NPPA
Natriuretic peptide A.
      
 0.720
EDN1
Endothelin 1.
      
 0.719
AGTR1
Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.715
ACE
Angiotensin-converting enzyme; Belongs to the peptidase M2 family.
      
 0.694
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.