GHSR protein (Ailuropoda melanoleuca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

GHSR

Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)

Predicted Functional Partners:

GHRL

0.996

GNG4

0.943

GNB2

0.939

GNB3

0.932

MRAP2

0.931

GNB5

0.927

GNG11

0.916

GNGT1

0.916

GNAS

0.915

GNGT2

0.909

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GHRL	GHSR	ENSAMEP00000016898	ENSAMEP00000001032	Uncharacterized protein.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.996
GHRL	GNG4	ENSAMEP00000016898	ENSAMEP00000003254	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.421
GHSR	GHRL	ENSAMEP00000001032	ENSAMEP00000016898	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.996
GHSR	GNAS	ENSAMEP00000001032	ENSAMEP00000013218	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	GNAS complex locus.	0.915
GHSR	GNB2	ENSAMEP00000001032	ENSAMEP00000015571	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 2.	0.939
GHSR	GNB3	ENSAMEP00000001032	ENSAMEP00000014773	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 3.	0.932
GHSR	GNB5	ENSAMEP00000001032	ENSAMEP00000007574	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 5.	0.927
GHSR	GNG11	ENSAMEP00000001032	ENSAMEP00000018737	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.916
GHSR	GNG4	ENSAMEP00000001032	ENSAMEP00000003254	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.943
GHSR	GNGT1	ENSAMEP00000001032	ENSAMEP00000018738	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.916
GHSR	GNGT2	ENSAMEP00000001032	ENSAMEP00000005422	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.909
GHSR	MRAP2	ENSAMEP00000001032	ENSAMEP00000012665	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Melanocortin 2 receptor accessory protein 2.	0.931
GNAS	GHSR	ENSAMEP00000013218	ENSAMEP00000001032	GNAS complex locus.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.915
GNAS	GNB2	ENSAMEP00000013218	ENSAMEP00000015571	GNAS complex locus.	G protein subunit beta 2.	0.956
GNAS	GNB3	ENSAMEP00000013218	ENSAMEP00000014773	GNAS complex locus.	G protein subunit beta 3.	0.956
GNAS	GNB5	ENSAMEP00000013218	ENSAMEP00000007574	GNAS complex locus.	G protein subunit beta 5.	0.904
GNAS	GNG11	ENSAMEP00000013218	ENSAMEP00000018737	GNAS complex locus.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.945
GNAS	GNG4	ENSAMEP00000013218	ENSAMEP00000003254	GNAS complex locus.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.987
GNAS	GNGT1	ENSAMEP00000013218	ENSAMEP00000018738	GNAS complex locus.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.931
GNAS	GNGT2	ENSAMEP00000013218	ENSAMEP00000005422	GNAS complex locus.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.961