STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (280 aa)    
Predicted Functional Partners:
LYN
Tyrosine-protein kinase.
   
 0.940
RAC2
Rac family small GTPase 2.
   
  0.906
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
 0.837
G1L1A9_AILME
Uncharacterized protein.
   
  0.713
RAC1
Rac family small GTPase 1.
   
  0.713
RAC3
Rac family small GTPase 3.
   
  0.713
PLCG1
Phosphoinositide phospholipase C.
     
 0.693
LCK
Tyrosine-protein kinase.
   
 0.605
HCK
Tyrosine-protein kinase.
   
 0.605
HIBADH
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
    
  0.604
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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