STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRUNE1Prune exopolyphosphatase 1. (453 aa)    
Predicted Functional Partners:
HDDC3
HD domain containing 3.
     
  0.900
IP6K1
Kinase; Belongs to the inositol phosphokinase (IPK) family.
      
 0.740
APRT
Adenine phosphoribosyltransferase.
     
 0.671
G1LA27_AILME
CRAL-TRIO domain-containing protein.
 
    
 0.576
CDKL5
Cyclin dependent kinase like 5.
      
 0.564
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
      
 0.529
KIF1A
Kinesin family member 1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.495
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
    
 
 0.478
CENPJ
Centromere protein J.
      
 0.447
SLC66A1
Solute carrier family 66 member 1.
      
 0.435
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.