Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RSPO1R-spondin 1. (262 aa)    
Predicted Functional Partners:
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
   
 0.993
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 0.989
RNF43
RING-type domain-containing protein.
    
 0.975
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
    
 0.899
ZNRF3
Zinc and ring finger 3.
    
 0.858
RSPO4
R-spondin 4.
     
 0.810
RSPO3
R-spondin 3.
     
  0.807
RSPO2
R-spondin 2.
     
 0.794
NOG
Noggin.
      
 0.767
WNT4
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.767
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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