STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DPH22-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (490 aa)    
Predicted Functional Partners:
DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.
   
0.991
DPH3
Diphthamide biosynthesis 3.
   
 0.979
DPH5
Diphthamide biosynthesis 5.
   
 0.953
DDX31
RNA helicase.
   
   0.773
G1L132_AILME
Uncharacterized protein.
    
 0.744
EEF2
Tr-type G domain-containing protein.
    
 0.744
G1LLY7_AILME
Uncharacterized protein.
    
 0.744
DNAJC24
DnaJ heat shock protein family (Hsp40) member C24.
   
 
 0.707
CCDC73
Coiled-coil domain containing 73.
      
 0.703
RRP9
Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein.
   
    0.665
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: medium (44%) [HD]