FBXO38 protein (Ailuropoda melanoleuca) - STRING interaction network

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Score

FBXO38

F-box protein 38. (1190 aa)

Predicted Functional Partners:

CUL1

0.945

USP7

0.860

TDRP

0.767

RNF169

0.743

KLHL22

0.722

KLF7

0.714

CUL3

0.688

G1L923_AILME

0.685

SKP1

0.685

MCMBP

0.642

Your Current Organism:

Ailuropoda melanoleuca

NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL1	CUL3	ENSAMEP00000003070	ENSAMEP00000012279	Cullin 1; Belongs to the cullin family.	Cullin 3; Belongs to the cullin family.	0.888
CUL1	FBXO38	ENSAMEP00000003070	ENSAMEP00000001215	Cullin 1; Belongs to the cullin family.	F-box protein 38.	0.945
CUL1	G1L923_AILME	ENSAMEP00000003070	ENSAMEP00000003392	Cullin 1; Belongs to the cullin family.	Uncharacterized protein; Belongs to the SKP1 family.	0.981
CUL1	KLHL22	ENSAMEP00000003070	ENSAMEP00000011753	Cullin 1; Belongs to the cullin family.	Kelch-like protein 22; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation. The BCR(KLHL22) ubiquitin ligase complex is also responsible for the amino acid-stim [...]	0.447
CUL1	SKP1	ENSAMEP00000003070	ENSAMEP00000018814	Cullin 1; Belongs to the cullin family.	S-phase kinase associated protein 1; Belongs to the SKP1 family.	0.981
CUL1	USP7	ENSAMEP00000003070	ENSAMEP00000011339	Cullin 1; Belongs to the cullin family.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.541
CUL3	CUL1	ENSAMEP00000012279	ENSAMEP00000003070	Cullin 3; Belongs to the cullin family.	Cullin 1; Belongs to the cullin family.	0.888
CUL3	FBXO38	ENSAMEP00000012279	ENSAMEP00000001215	Cullin 3; Belongs to the cullin family.	F-box protein 38.	0.688
CUL3	G1L923_AILME	ENSAMEP00000012279	ENSAMEP00000003392	Cullin 3; Belongs to the cullin family.	Uncharacterized protein; Belongs to the SKP1 family.	0.869
CUL3	KLHL22	ENSAMEP00000012279	ENSAMEP00000011753	Cullin 3; Belongs to the cullin family.	Kelch-like protein 22; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation. The BCR(KLHL22) ubiquitin ligase complex is also responsible for the amino acid-stim [...]	0.974
CUL3	SKP1	ENSAMEP00000012279	ENSAMEP00000018814	Cullin 3; Belongs to the cullin family.	S-phase kinase associated protein 1; Belongs to the SKP1 family.	0.869
CUL3	USP7	ENSAMEP00000012279	ENSAMEP00000011339	Cullin 3; Belongs to the cullin family.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.671
FBXO38	CUL1	ENSAMEP00000001215	ENSAMEP00000003070	F-box protein 38.	Cullin 1; Belongs to the cullin family.	0.945
FBXO38	CUL3	ENSAMEP00000001215	ENSAMEP00000012279	F-box protein 38.	Cullin 3; Belongs to the cullin family.	0.688
FBXO38	G1L923_AILME	ENSAMEP00000001215	ENSAMEP00000003392	F-box protein 38.	Uncharacterized protein; Belongs to the SKP1 family.	0.685
FBXO38	KLF7	ENSAMEP00000001215	ENSAMEP00000015959	F-box protein 38.	Kruppel like factor 7.	0.714
FBXO38	KLHL22	ENSAMEP00000001215	ENSAMEP00000011753	F-box protein 38.	Kelch-like protein 22; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation. The BCR(KLHL22) ubiquitin ligase complex is also responsible for the amino acid-stim [...]	0.722
FBXO38	MCMBP	ENSAMEP00000001215	ENSAMEP00000010764	F-box protein 38.	Minichromosome maintenance complex binding protein.	0.642
FBXO38	RNF169	ENSAMEP00000001215	ENSAMEP00000018110	F-box protein 38.	Ring finger protein 169.	0.743
FBXO38	SKP1	ENSAMEP00000001215	ENSAMEP00000018814	F-box protein 38.	S-phase kinase associated protein 1; Belongs to the SKP1 family.	0.685