Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
RUNDC3BRUN domain containing 3B. (433 aa)    
Predicted Functional Partners:
AP2S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
   0.581
CROT
Carnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family.
      
 0.575
DMTF1
Cyclin D binding myb like transcription factor 1.
      
 0.546
UVRAG
UV radiation resistance associated.
    
 0.544
SLC25A40
Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.500
SLC25A39
Solute carrier family 25 member 39; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.500
AP2A2
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
 
 0.494
KCTD20
Potassium channel tetramerization domain containing 20.
      
 0.490
AP2M1
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
   
   0.486
ADAM22
ADAM metallopeptidase domain 22.
      
 0.479
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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