Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PANDA_017594Uncharacterized protein. (95 aa)    
Predicted Functional Partners:
ALK
ALK receptor tyrosine kinase.
 
      0.881
EML4
EMAP like 4.
   
 0.852
KRAS
KRAS proto-oncogene, GTPase.
    
 0.819
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.818
PLCG1
Phosphoinositide phospholipase C.
    
 0.813
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.787
PTN
Pleiotrophin.
    
 0.778
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.777
ALKAL2
ALK and LTK ligand 2.
    
 0.775
G1L334_AILME
Uncharacterized protein.
 
     0.771
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.