Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)    
Predicted Functional Partners:
FZD3
Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.970
FZD4
Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.
  
 
 0.965
LRP6
LDL receptor related protein 6.
    
 0.957
FZD6
Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.957
FZD2
Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.
  
 
 0.956
PORCN
Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family.
    
 0.955
FZD7
Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.
  
 
 0.955
WIF1
WNT inhibitory factor 1.
    
 0.954
SFRP2
Secreted frizzled related protein 2.
    
 0.952
SFRP4
Secreted frizzled related protein 4.
    
 0.947
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
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