Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WDR59WD repeat domain 59. (974 aa)    
Predicted Functional Partners:
SEH1L
SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family.
    
 0.999
NPRL3
NPR3 like, GATOR1 complex subunit.
    
 0.998
DEPDC5
DEP domain-containing protein.
   
 0.998
WDR24
WD repeat domain 24.
   
0.998
NPRL2
NPR2 like, GATOR1 complex subunit.
    
 0.998
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
    
 0.998
MIOS
Meiosis regulator for oocyte development.
    
 0.997
CASTOR1
Cytosolic arginine sensor for mTORC1 subunit 1.
    
 0.996
SESN2
Sestrin 2.
    
 0.995
ITFG2
Integrin alpha FG-GAP repeat containing 2.
    
 0.988
Your Current Organism:
Ailuropoda melanoleuca
NCBI taxonomy Id: 9646
Other names: A. melanoleuca, giant panda
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.